Do You Understand The Detection Of Alcohol Abuse Markers?

Alcohol abuse is one of the social problems that exist in many countries. For many years, scholars at home and abroad have been working hard to find suitable biomarkers to evaluate alcohol abuse. Ethyl Glucuronic acid (EtG) is an important indicator of alcohol abuse that has been widely concerned in recent years. The correlation between EtG content and ethanol intake, the use of EtG as a characteristic indicator of ethanol intake to infer drinking time, the use of EtG content to distinguish whether to drink excessively, and the identification of ethanol sources in corpses are of great significance.
Why test EtG when ethanol can be directly detected?
In the identification of drunk Hit and run or drunk driving, due to the rapid metabolism of ethanol in the body, ethanol is generally not detected in the body 6-8 hours after drinking, especially in the case of drunk driving Hit and run, the time interval between blood sampling and the accident is too long, and no ethanol component has been detected in the blood, but EtG can be detected, which is a landmark product of ethanol metabolism in the human body, It is formed by the combination of ethanol and Uracil nucleoside 5 '- diphosphate Glucuronic acid.